Pyruvate Dehydrogenase Reaction

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Zhang Xin
Hillman The Anchor Center

Pyruvate dehydrogenase is the first component enzyme of pyruvate dehydrogenase complex (PDC). The pyruvate dehydrogenase complex contributes to transforming pyruvate into acetyl-CoA by a process called pyruvate decarboxylation . Acetyl-CoA may then be used in the citric acid cycle to carry out cellular respiration , so pyruvate dehydrogenase contributes to linking the glycolysis metabolic pathway to the citric acid cycle and releasing energy via NADH .